Receptor-Mediated Binding and Internalization of Toxins and by John Middlebrook

By John Middlebrook

Receptor-Mediated Binding and Internalization of poisons and Hormones offers the court cases of a convention performed for the aim of exploring relationships among hormones and pollutants, particularly, receptor-mediated internalization of poisons and hormones and the function of this internalization in message transmission and biodegradatory strategies.
This ebook is split into 3 sections, with the 1st targeting version structures of internalization. It offers pictorial illustrations of the receptor-mediated endocytosis of low-density lipoprotein through lined areas of membrane and discusses the receptor for lysosomal enzymes at the floor of cultured fibroblasts. the second one part specializes in pollutants and hormones and discusses such issues as receptor-mediated internalization of diphtheria toxin, diphtheria toxin interactions with an inhibitory task from plasma membranes, and uptake mechanisms for ADP-ribosylating pollutants. The 3rd and ultimate part makes a speciality of hybrids and discusses such themes as chimeric pollution containing fragment A from diphtheria toxin, directed access of hybrid proteins into cells through trade receptors, and a hybrid protein of monoclonal anti-THY 1.2 and diphtheria toxin fragment A.
This publication may be of curiosity to practitioners within the fields of endocrinology, phone biology, and molecular genetics.

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